Multiple exposure to chemicals.

  title={Multiple exposure to chemicals.},
  author={M Ikeda},
  journal={Regulatory toxicology and pharmacology : RTP},
  volume={8 4},
  • M Ikeda
  • Published 1988 in Regulatory toxicology and pharmacology : RTP
In order to evaluate the possible interactive effects of simultaneous exposure to more than one chemical, leading toxicological journals over the period 1981-1987 were reviewed for articles on combined exposure. Additive effects or less or no interaction were reported in most cases. More than additive effects were reported in 20 out of 104 studies (excluding alcohol), but this conclusion was sometimes not supported by the data. Examples of studies on changes in metabolisms caused by multiple… CONTINUE READING