Multiple essential roles for primary cilia in heart development

@inproceedings{Willaredt2012MultipleER,
  title={Multiple essential roles for primary cilia in heart development},
  author={Marc August Willaredt and Karin Gorgas and Humphrey A R Gardner and Kerry Lee Tucker},
  booktitle={Cilia},
  year={2012}
}
  • Marc August Willaredt, Karin Gorgas, +1 author Kerry Lee Tucker
  • Published in Cilia 2012
  • Biology, Medicine
  • BackgroundThe primary cilium is a microtubule-based, plasma membrane-ensheathed protrusion projecting from the basal bodies of almost all cell types in the mammalian body. In the past several years a plethora of papers has indicated a crucial role for primary cilia in the development of a wide variety of organs. We have investigated heart development in cobblestone, a hypomorphic allele of the gene encoding the intraflagellar transport protein Ift88, and uncovered a number of the most common… CONTINUE READING

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