Multiple enzymatic activities associated with severe acute respiratory syndrome coronavirus helicase.

  title={Multiple enzymatic activities associated with severe acute respiratory syndrome coronavirus helicase.},
  author={Konstantin A Ivanov and Volker Thiel and Jessika C Dobbe and Yvonne van der Meer and Eric J. Snijder and John Ziebuhr},
  journal={Journal of virology},
  volume={78 11},
Severe acute respiratory syndrome coronavirus (SARS-CoV), a newly identified group 2 coronavirus, is the causative agent of severe acute respiratory syndrome, a life-threatening form of pneumonia in humans. Coronavirus replication and transcription are highly specialized processes of cytoplasmic RNA synthesis that localize to virus-induced membrane structures and were recently proposed to involve a complex enzymatic machinery that, besides RNA-dependent RNA polymerase, helicase, and protease… CONTINUE READING
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