Multiple endocrine syndrome type I. Clinical, laboratory findings, and management in five families.

@article{Samaan1989MultipleES,
  title={Multiple endocrine syndrome type I. Clinical, laboratory findings, and management in five families.},
  author={Naguib Samaan and S Ouais and Nelson G. Ord{\'o}{\~n}ez and U A Choksi and Rena V. Sellin and Robert C. Hickey},
  journal={Cancer},
  year={1989},
  volume={64 3},
  pages={
          741-52
        }
}
The clinical features of 20 patients from five families with multiple endocrine neoplasia syndrome type I (MEN-I) were studied. Nineteen patients (95%) had hyperparathyroidism. Five patients who had a diagnosis during surgery of adenoma and who had fewer than 3.5 glands removed had recurrence of hypercalcemia after surgery. Fourteen patients (70%) had pancreatic islet cell tumors. All had one or more elevated serum polypeptide hormones, and six had symptoms related to the hormones produced… CONTINUE READING
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