Multiple endocrine abnormalities of the growth hormone and insulin-like growth factor axis in prepubertal children with exogenous obesity: effect of short- and long-term weight reduction.

@article{Argente1997MultipleEA,
  title={Multiple endocrine abnormalities of the growth hormone and insulin-like growth factor axis in prepubertal children with exogenous obesity: effect of short- and long-term weight reduction.},
  author={Jes{\'u}s Argente and N Caballo and Vicente Barrios and J. Sanchez del Pozo and Mar{\'i}a Teresa Giner Mu{\~n}oz and Julie A Chowen and Marcelino Hern{\'a}ndez},
  journal={The Journal of clinical endocrinology and metabolism},
  year={1997},
  volume={82 7},
  pages={2076-83}
}
We have studied the GH-insulin-like growth factor (IGF) axis in prepubertal children with exogenous obesity at the time of clinical diagnosis and at two time points during weight reduction on a calorie-restricted diet. Spontaneous GH secretion, IGF-I, free IGF-I (fIGF-I), IGF-II, their binding proteins (IGFBP-1, IGFBP-2, and IGFBP-3), and GH-binding protein (GHBP) values at the time of clinical diagnosis (n = 65), after a 25% decrease in the body mass index (BMI) expressed as the SD score (BMI… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 36 extracted citations

Effects of growth hormone treatment in obese prepubertal boys.

The Journal of clinical endocrinology and metabolism • 2000
View 4 Excerpts
Highly Influenced

Reduced Growth Hormone Secretion is Associated with Nonalcoholic Fatty Liver Disease in Obese Children.

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme • 2018
View 2 Excerpts

Similar Papers

Loading similar papers…