Multiple displacement amplification for preimplantation genetic diagnosis of fragile X syndrome.

@article{Lee2011MultipleDA,
  title={Multiple displacement amplification for preimplantation genetic diagnosis of fragile X syndrome.},
  author={H-S Lee and Min Jee Kim and Chai K. Lim and Jae Won Cho and In Ok Song and Inn Soo Kang},
  journal={Genetics and molecular research : GMR},
  year={2011},
  volume={10 4},
  pages={2851-9}
}
Preimplantation genetic diagnosis (PGD) has become an assisted reproductive technique for couples that have genetic risks. Despite the many advantages provided by PGD, there are several problems, including amplification failure, allele drop-out and amplification inefficiency. We evaluated multiple displacement amplification (MDA) for PGD of the fragile X syndrome. Whole genome amplification was performed using MDA. MDA products were subjected to fluorescent PCR of fragile X mental retardation-1… CONTINUE READING
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Efficacy of duplex-nested PCR and fluorescent PCR in the preimplantation genetic diagnosis for Duchenne muscular dystrophy

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