Multiple deletions of the osmolyte transporters BetL, Gbu, and OpuC of Listeria monocytogenes affect virulence and growth at high osmolarity.

@article{WemekampKamphuis2002MultipleDO,
  title={Multiple deletions of the osmolyte transporters BetL, Gbu, and OpuC of Listeria monocytogenes affect virulence and growth at high osmolarity.},
  author={Henrike H. Wemekamp-Kamphuis and Jeroen A. Wouters and Roy D. Sleator and Cormac G. M. Gahan and C. Ray Hill and Tjakko Abee},
  journal={Applied and environmental microbiology},
  year={2002},
  volume={68 10},
  pages={4710-6}
}
The success of Listeria monocytogenes as a food-borne pathogen owes much to its ability to survive a variety of stresses, both in the food environment and, after ingestion, within the animal host. Growth at high salt concentrations is attributed mainly to the accumulation of organic solutes such as glycine betaine and carnitine. We characterized L. monocytogenes LO28 strains with single, double, and triple deletions in the osmolyte transport systems BetL, Gbu, and OpuC. When single deletion… CONTINUE READING

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Analysis of the role of betL in contributing to the growth and survival of Listeria monocytogenes LO28

  • R. D. Sleator, C.G.M. Gahan, B. O’Driscoll, C. Hill
  • Int. J. Food Microbiol
  • 2000
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