Multiple cytokines regulate the NK gene complex-encoded receptor repertoire of mature NK cells and T cells.

@article{Gays2005MultipleCR,
  title={Multiple cytokines regulate the NK gene complex-encoded receptor repertoire of mature NK cells and T cells.},
  author={Frances Gays and Kimberley Martin and Rupert Kenefeck and Jonathan G. Aust and Colin G. Brooks},
  journal={Journal of immunology},
  year={2005},
  volume={175 5},
  pages={2938-47}
}
Mature NK cells comprise a highly diverse population of lymphocytes that express different permutations of receptors to facilitate recognition of diseased cells and perhaps pathogens themselves. Many of these receptors, such as those belonging to the NKRP1, NKG2, and Ly49 families are encoded in the NK gene complex (NKC). It is generally thought that these NKC-encoded receptors are acquired by a poorly understood stochastic mechanism, which operates exclusively during NK cell development, and… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 30 extracted citations

Similar Papers

Loading similar papers…