Multiple cytokine and acute-phase protein gene transcription in West Greenland sledge dogs (Canis familiaris) dietary exposed to organic environmental pollutants.

@article{Sonne2007MultipleCA,
  title={Multiple cytokine and acute-phase protein gene transcription in West Greenland sledge dogs (Canis familiaris) dietary exposed to organic environmental pollutants.},
  author={Christian Sonne and Sonja Fonfara and Rune Dietz and Maja Harder Kirkegaard and Robert J Letcher and Soheila Shahmiri and Sten Morten Andersen and Per M\oller},
  journal={Archives of environmental contamination and toxicology},
  year={2007},
  volume={53 1},
  pages={110-8}
}
Exposure levels of persistent organic pollutants, such as polychlorinated biphenyls and DDTs, are high in Arctic apex predators and Inuit peoples and are suspected to have negative impacts on their immune systems. We conducted a controlled generational study on liver tissue and ethylenediaminetetraacetic acid blood cytokine and acute-phase protein (APP) mRNA expressions using reverse transcriptionase-polymerase chain reaction in West Greenland sledge dogs (Canis familiaris); contaminated minke… CONTINUE READING
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