Multiple cotton wool spots following bone marrow transplantation for treatment of acute lymphatic leukaemia.

@article{Gloor1985MultipleCW,
  title={Multiple cotton wool spots following bone marrow transplantation for treatment of acute lymphatic leukaemia.},
  author={Balder Gloor and Alois A Gratwohl and H D Hahn and Serge Kretzschmar and Yohan Robert and Bruno Speck and Basil Daicker},
  journal={The British journal of ophthalmology},
  year={1985},
  volume={70 2},
  pages={157}
}
Three patients with acute lymphatic leukaemia developed visual impairment due to occlusion of small retinal vessels with multiple cotton wool spots after treatment which included whole body and skull irradiation followed by bone marrow transplantation and cyclosporin A. Withdrawal of cyclosporin A and treatment with corticosteroids was followed by recovery of visual acuity. This retinopathy and the retinal changes seen in the immunodeficiency syndrome are thought to be closely related. The… CONTINUE READING