Multiple contributions of peroxisomal metabolic function to fungal pathogenicity in Colletotrichum lagenarium.

@article{Asakura2006MultipleCO,
  title={Multiple contributions of peroxisomal metabolic function to fungal pathogenicity in Colletotrichum lagenarium.},
  author={Makoto Asakura and Tetsuro Okuno and Yoshitaka Takano},
  journal={Applied and environmental microbiology},
  year={2006},
  volume={72 9},
  pages={6345-54}
}
In Colletotrichum lagenarium, which is the causal agent of cucumber anthracnose, PEX6 is required for peroxisome biogenesis and appressorium-mediated infection. To verify the roles of peroxisome-associated metabolism in fungal pathogenicity, we isolated and functionally characterized ICL1 of C. lagenarium, which encodes isocitrate lyase involved in the glyoxylate cycle in peroxisomes. The icl1 mutants failed to utilize fatty acids and acetate for growth. Although Icl1 has no typical peroxisomal… CONTINUE READING

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