Multiple cis-acting regulatory regions are required for restricted spatio-temporal Hoxa5 gene expression.

@article{Larochelle1999MultipleCR,
  title={Multiple cis-acting regulatory regions are required for restricted spatio-temporal Hoxa5 gene expression.},
  author={Christian Larochelle and Maxime Tremblay and Denis Bernier and Jos{\'e}e Aubin and Lucie Jeannotte},
  journal={Developmental dynamics : an official publication of the American Association of Anatomists},
  year={1999},
  volume={214 2},
  pages={
          127-40
        }
}
Genetic analyses have revealed the essential role of the murine Hoxa5 gene for the correct specification of the cervical and upper thoracic region of the skeleton, and for the normal organogenesis and function of the respiratory tract, both structures expressing Hoxa5 during embryogenesis. To understand how the expression domains of the Hoxa5 gene are established during development, we have analyzed the cis-acting control regions mediating Hoxa5 gene expression using a transgenic approach. Four… CONTINUE READING
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