Multiple ciguatoxins present in Indian Ocean reef fish.

@article{Hamilton2002MultipleCP,
  title={Multiple ciguatoxins present in Indian Ocean reef fish.},
  author={Brett R. Hamilton and Mira Devi Hurbungs and Alun R. Jones and Richard James Lewis},
  journal={Toxicon : official journal of the International Society on Toxinology},
  year={2002},
  volume={40 9},
  pages={
          1347-53
        }
}
Optimised gradient reversed-phase high-performance liquid chromatography electrospray ionisation mass spectrometry (LC/MS) methods, in combination with a [3H]-brevetoxin binding assay (RLB), revealed multiple ciguatoxins in a partially purified extract of a highly toxic Lutjanus sebae (red emperor) from the Indian Ocean. Two major ciguatoxins of 1140.6 Da (I-CTX-1 and -2) and two minor ciguatoxins of 1156.6 Da (I-CTX-3 and -4) were identified. Accurate mass analysis revealed that I-CTX-1 and -2… CONTINUE READING
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