Multiple breath helium dilution measurement of lung volumes in adults.

  title={Multiple breath helium dilution measurement of lung volumes in adults.},
  author={Raya S. Brown and David E. Leith and Paul L. Enright},
  journal={The European respiratory journal},
  volume={11 1},
This manuscript recommends techniques (methodology) for the measurement of total lung capacity (TLC), functional residual capacity (FRC) and residual volume (RV) in adults using the closed-circuit helium dilution method. Lung volumes were first measured using a hydrogen gas dilution technique about 200 yrs ago. Helium replaced hydrogen for safety reasons 40–50 yrs ago when clinicians started to use the test [1]. Since its description in 1940, the nitrogen washout method has been shown to give… CONTINUE READING


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Infectious disease precautions and measurements of absolute lung volumes

  • JL Clausen
  • Eur Respir J
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