Multiple-bond kinetics from single-molecule pulling experiments: evidence for multiple NCAM bonds.

@article{Hukkanen2005MultiplebondKF,
  title={Multiple-bond kinetics from single-molecule pulling experiments: evidence for multiple NCAM bonds.},
  author={E J Hukkanen and Julie A Wieland and Alan Gewirth and Deborah E. Leckband and Richard D. Braatz},
  journal={Biophysical journal},
  year={2005},
  volume={89 5},
  pages={3434-45}
}
The kinetic parameters of single bonds between neural cell adhesion molecules were determined from atomic force microscope measurements of the forced dissociation of the homophilic protein-protein bonds. The analytical approach described provides a systematic procedure for obtaining rupture kinetics for single protein bonds from bond breakage frequency… CONTINUE READING