Multiple alphaII-spectrin breakdown products distinguish calpain and caspase dominated necrotic and apoptotic cell death pathways

@article{Zhang2009MultipleAB,
  title={Multiple alphaII-spectrin breakdown products distinguish calpain and caspase dominated necrotic and apoptotic cell death pathways},
  author={Zhiqun Zhang and S. F. Larner and Ming Cheng Liu and Wenrong Zheng and Ronald L. Hayes and Kevin K. W. Wang},
  journal={Apoptosis},
  year={2009},
  volume={14},
  pages={1289-1298}
}
Apoptosis and oncotic necrosis in neuronal and glial cells have been documented in many neurological diseases. Distinguishing between these two major types of cell death in different neurological diseases is needed in order to better reveal the injury mechanisms so as to open up opportunities for therapy development. Accumulating evidence suggests apoptosis and oncosis epitomize the extreme ends of a broad spectrum of morphological and biochemical events. Biochemical markers that can… CONTINUE READING