• Chemistry, Medicine
  • Published in
    Canadian journal of…
    1995
  • DOI:10.1139/y95-134

Multiple affinity and guanine nucleotide sensitive forms of the calcitonin gene related peptide (CGRP) receptor.

@article{Chatterjee1995MultipleAA,
  title={Multiple affinity and guanine nucleotide sensitive forms of the calcitonin gene related peptide (CGRP) receptor.},
  author={Tapan Kumar Chatterjee and Rory A. Fisher},
  journal={Canadian journal of physiology and pharmacology},
  year={1995},
  volume={73 7},
  pages={
          968-73
        }
}
Calcitonin gene related peptide (CGRP) is a novel neuropeptide with an impressive array of biological actions consistent with its diverse tissue distribution and suggested role as neurotransmitter or neuromodulator. Binding sites for CGRP with properties consistent with those of receptors are present in both central and peripheral tissues. Radioligand binding studies were performed to investigate the fundamental processes underlying CGRP receptor activation and signaling following agonist… CONTINUE READING