Multiple Streptococcus mutans Genes Are Involved in Biofilm Formation.

  title={Multiple Streptococcus mutans Genes Are Involved in Biofilm Formation.},
  author={Akihiro Yoshida and Howard K. Kuramitsu},
  journal={Applied and environmental microbiology},
  volume={68 12},
Streptococcus mutans has been strongly implicated as the principal etiological agent in dental caries. One of the important virulence properties of these organisms is their ability to form biofilms known as dental plaque on tooth surfaces. Since the roles of sucrose and glucosyltransferases in S. mutans biofilm formation have been well documented, we focused our attention on sucrose-independent factors. We have initially identified several mutants that appear to be defective in biofilm… CONTINUE READING


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