Multiple Sclerosis and Antibodies against KIR4.1.

@article{Proebstel2016MultipleSA,
  title={Multiple Sclerosis and Antibodies against KIR4.1.},
  author={Anne-Katrin Proebstel and Jens Kuhle and Anne-Catherine Lecourt and Isabelle Vock and Nicholas S R Sanderson and Ludwig Kappos and Tobias J Derfuss},
  journal={The New England journal of medicine},
  year={2016},
  volume={374 15},
  pages={1496-8}
}
n engl j med 374;15 nejm.org April 14, 2016 at our center. None of the samples from either the multiple sclerosis group or the control group showed KIR4.1 reactivity, and no significant between-group difference (P>0.05) was established (Fig. 1A). The enrichment of low-glycosylated KIR4.1 tetramer isoforms was confirmed with the 20F9 monoclonal antibody (P = 0.002) (Fig. 1B). Taken together, these results indicate that autoantibodies against KIR4.1 may not be specific for multiple sclerosis… CONTINUE READING
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