Multiple Sclerosis - A Vascular Etiology?

@article{Weir2010MultipleS,
  title={Multiple Sclerosis - A Vascular Etiology?},
  author={Bryce K. A. Weir},
  journal={Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques},
  year={2010},
  volume={37},
  pages={745 - 757}
}
  • B. Weir
  • Published 1 November 2010
  • Medicine
  • Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques
Abstract From the earliest pathological studies the perivenular localization of the demyelination in multiple sclerosis (MS) has been observed. It has recently been suggested that obstructions to venous flow or inadequate venous valves in the great veins in the neck, thorax and abdomen can cause damaging backflow into the cerebral and spinal cord circulations. Paolo Zamboni and colleagues have demonstrated abnormal venous circulation in some multiple sclerosis patients using non-invasive… 
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