• DOI:10.1016/j.neuron.2018.01.021
Corpus ID: 3499974

Multiple Sclerosis: Mechanisms and Immunotherapy

@article{BaecherAllan2018MultipleSM,
  title={Multiple Sclerosis: Mechanisms and Immunotherapy},
  author={C. Baecher-Allan and Belinda J. Kaskow and H. Weiner},
  journal={Neuron},
  year={2018},
  volume={97},
  pages={742-768}
}

C. Baecher-Allan, Belinda J. Kaskow, H. Weiner

Published 2018

Medicine

Neuron

Multiple sclerosis (MS) is an autoimmune disease triggered by environmental factors that act on a genetically susceptible host. It features three clinical stages: a pre-clinical stage detectable only by MRI; a relapsing-remitting (RRMS) stage characterized by episodes of neurologic dysfunction followed by resolution; and a progressive stage, which usually evolves from the relapsing stage. Advances in our understanding of the immune mechanisms that contribute to MS have led to more than ten FDA… CONTINUE READING

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