Multiple PU.1 sites cooperate in the regulation of p40(phox) transcription during granulocytic differentiation of myeloid cells.

Abstract

The p40(phox) protein, a regulatory component of the phagocyte NADPH oxidase, is preferentially expressed in cells of myeloid lineage. We investigated transcriptional regulation of the p40(phox) gene in HL-60 myeloid cells. Deletion analysis of approximately 6 kb of the 5'-flanking sequence of the gene demonstrated that the proximal 106 base pair of the… (More)

Topics

9 Figures and Tables

Cite this paper

@article{Li2002MultiplePS, title={Multiple PU.1 sites cooperate in the regulation of p40(phox) transcription during granulocytic differentiation of myeloid cells.}, author={Sen-lin Li and Anthony J Valente and Mei Qiang and Werner Schlegel and Maria J Gamez and Robert A. Clark}, journal={Blood}, year={2002}, volume={99 12}, pages={4578-87} }