Multiple Loci modulate opioid therapy response for cancer pain.

Abstract

PURPOSE Patients treated with opioid drugs for cancer pain experience different relief responses, raising the possibility that genetic factors play a role in opioid therapy outcome. In this study, we tested the hypothesis that genetic variations may control individual response to opioid drugs in cancer patients. EXPERIMENTAL DESIGN We tested 1 million… (More)
DOI: 10.1158/1078-0432.CCR-10-3028

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