Multiple Hepcidins in a Teleost Fish, Dicentrarchus labrax: Different Hepcidins for Different Roles.

@article{Neves2015MultipleHI,
  title={Multiple Hepcidins in a Teleost Fish, Dicentrarchus labrax: Different Hepcidins for Different Roles.},
  author={Jo{\~a}o V Neves and Carolina Caldas and In{\^e}s Passos Vieira and Miguel Filipe Ramos and Pedro Nuno Rodrigues},
  journal={Journal of immunology},
  year={2015},
  volume={195 6},
  pages={2696-709}
}
Teleost fish rely heavily on their innate immunity for an adequate response against pathogens and environmental challenges, with the production of antimicrobial peptides being one of their first lines of defense. Among those is hepcidin, a small cysteine-rich antimicrobial peptide that is also the key regulator of iron metabolism. Although most mammals possess a single hepcidin gene, with a dual role in both iron metabolism regulation and antimicrobial response, many teleost fish present… CONTINUE READING

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