Multiple GTPases participate in the assembly of the large ribosomal subunit in Bacillus subtilis.

@article{Schaefer2006MultipleGP,
  title={Multiple GTPases participate in the assembly of the large ribosomal subunit in Bacillus subtilis.},
  author={Laura K Schaefer and William C Uicker and Catherine Wicker-Planquart and Anne-Emmanuelle Foucher and Jean-Michel Jault and Robert A Britton},
  journal={Journal of bacteriology},
  year={2006},
  volume={188 23},
  pages={8252-8}
}
GTPases have been demonstrated to be necessary for the proper assembly of the ribosome in bacteria and eukaryotes. Here, we show that the essential GTPases YphC and YsxC are required for large ribosomal subunit biogenesis in Bacillus subtilis. Sucrose density gradient centrifugation of large ribosomal subunits isolated from YphC-depleted cells and YsxC-depleted cells indicates that they are similar to the 45S intermediate previously identified in RbgA-depleted cells. The sedimentation of the… CONTINUE READING
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