Multiple Epstein-Barr virus infections in healthy individuals.

  title={Multiple Epstein-Barr virus infections in healthy individuals.},
  author={Dennis M. Walling and Abigail Leigh Brown and Wiguins Etienne and Wendy A. Keitel and Paul D. Ling},
  journal={Journal of virology},
  volume={77 11},
We employed a newly developed genotyping technique with direct representational detection of LMP-1 gene sequences to study the molecular epidemiology of Epstein-Barr virus (EBV) infection in healthy individuals. Infections with up to five different EBV genotypes were found in two of nine individuals studied. These results support the hypothesis that multiple EBV infections of healthy individuals are common. The implications for the development of an EBV vaccine are discussed. 
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