Multiple Biomarkers for the Prediction of First Major Cardiovascular Events and Death

  title={Multiple Biomarkers for the Prediction of First Major Cardiovascular Events and Death},
  author={T. Wang and P. Gona and M. G. Larson and G. Tofler and D. Levy and C. Newton‐Cheh and P. Jacques and N. Rifai and J. Selhub and S. Robins and Emelia J Benjamin and R. D'Agostino and Ramachandran S. Vasan},
  journal={The New England Journal of Medicine},
  • T. Wang, P. Gona, +10 authors Ramachandran S. Vasan
  • Published 2006
  • Medicine
  • The New England Journal of Medicine
  • BACKGROUND: Few investigations have evaluated the incremental usefulness of multiple biomarkers from distinct biologic pathways for predicting the risk of cardiovascular events. METHODS: We measured 10 biomarkers in 3209 participants attending a routine examination cycle of the Framingham Heart Study: the levels of C-reactive protein, B-type natriuretic peptide, N-terminal pro-atrial natriuretic peptide, aldosterone, renin, fibrinogen, D-dimer, plasminogen-activator inhibitor type 1, and… CONTINUE READING
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