Multiple Amphiphysin II Splice Variants Display Differential Clathrin Binding: Identification of Two Distinct Clathrin‐Binding Sites

@article{Ramjaun1998MultipleAI,
  title={Multiple Amphiphysin II Splice Variants Display Differential Clathrin Binding: Identification of Two Distinct Clathrin‐Binding Sites},
  author={A. R. Ramjaun and P. McPherson},
  journal={Journal of Neurochemistry},
  year={1998},
  volume={70}
}
Abstract: Amphiphysin I and II are nerve terminal‐enriched proteins that display src homology 3 domain‐mediated interactions with dynamin and synaptojanin. It has been demonstrated that the amphiphysins also bind to clathrin, and we have proposed that this interaction may help to target synaptojanin and dynamin to sites of synaptic vesicle endocytosis. To understand better this potential functional role, we have begun to characterize clathrin‐amphiphysin interactions. Using PCR from adult human… Expand
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