Multiphoton excited fabrication of collagen matrixes cross-linked by a modified benzophenone dimer: bioactivity and enzymatic degradation.

@article{Basu2005MultiphotonEF,
  title={Multiphoton excited fabrication of collagen matrixes cross-linked by a modified benzophenone dimer: bioactivity and enzymatic degradation.},
  author={Swarna Basu and Lawrence P Cunningham and George D. Pins and Katie Ann Bush and Rosa Taboada and Amy R Howell and Jun Wang and Paul J Campagnola},
  journal={Biomacromolecules},
  year={2005},
  volume={6 3},
  pages={1465-74}
}
Multiphoton excited (MPE) photochemistry is used to fabricate model tissue engineering scaffolds directly from types I, II, and IV collagen. A modified benzophenone dimer (BPD) provides the photoactivation and becomes incorporated into the resulting collagen matrixes. Unlike xanthene photochemistries, the benzophenone dimer can be used in acidic environments, where most forms of collagen have the greatest solubility. The minimum feature sizes are investigated by using two- and three-photon… CONTINUE READING

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