Multiphasic modification of intrinsic functional connectivity of the rat brain during increasing levels of propofol

@article{Liu2013MultiphasicMO,
  title={Multiphasic modification of intrinsic functional connectivity of the rat brain during increasing levels of propofol},
  author={Xiping Liu and Siveshigan Pillay and Rupeng Li and Jeannette A. Vizuete and Kimberly R. Pechman and Kathleen M. Schmainda and Anthony G. Hudetz},
  journal={NeuroImage},
  year={2013},
  volume={83},
  pages={581-92}
}
The dose-dependent effects of anesthetics on brain functional connectivity are incompletely understood. Resting-state functional magnetic resonance imaging (rsfMRI) is widely used to assess the functional connectivity in humans and animals. Propofol is an anesthetic agent with desirable characteristics for functional neuroimaging in animals but its dose-dependent effects on rsfMRI functional connectivity have not been determined. Here we tested the hypothesis that brain functional connectivity… CONTINUE READING
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