Multiobjective evolutionary optimisation for surface-enhanced Raman scattering.

  title={Multiobjective evolutionary optimisation for surface-enhanced Raman scattering.},
  author={Roger M. Jarvis and William Rowe and Nicola R Yaffe and Richard O'Connor and Joshua D. Knowles and Ewan W Blanch and Royston Goodacre},
  journal={Analytical and bioanalytical chemistry},
  volume={397 5},
In most optimisation experiments, a single parameter is first optimised before a second and then third one are subsequently modified to give the best result. By contrast, we believe that simultaneous multiobjective optimisation is more powerful; therefore, an optimisation of the experimental conditions for the colloidal SERS detection of L-cysteine was carried out. Six aggregating agents and three different colloids (citrate, borohydride and hydroxylamine reduced silver) were tested over a wide… CONTINUE READING