Multimodal therapy for limited small-cell lung cancer: a randomized study of induction combination chemotherapy with or without thoracic radiation in complete responders; and with wide-field versus reduced-field radiation in partial responders: a Southwest Oncology Group Study.

@article{Kies1987MultimodalTF,
  title={Multimodal therapy for limited small-cell lung cancer: a randomized study of induction combination chemotherapy with or without thoracic radiation in complete responders; and with wide-field versus reduced-field radiation in partial responders: a Southwest Oncology Group Study.},
  author={Merrill S. Kies and Jo{\~a}o Gilberto S Mira and John J. Crowley and T. Timothy Chen and Richard Pazdur and P N Grozea and Saul E. Rivkin and Charles Arthur Coltman and John H. Ward and Robert B. Livingston},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={1987},
  volume={5 4},
  pages={592-600}
}
In 1979 we initiated a phase III study in the Southwest Oncology Group (SWOG) which was designed to determine the value of chest radiation in limited-stage small-cell lung cancer patients achieving complete response after induction chemotherapy, and to test the use of wide-field v more limited-volume radiation in patients with partial responses (PRs) and patients with stable disease (SD). The induction chemotherapy (VMV-VAC) consisted of vincristine, 2 mg intravenously (IV) every week for six… CONTINUE READING
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