Multimodal neuroimaging evidence of alterations in cortical structure and function in HIV-infected older adults.

@article{Wilson2015MultimodalNE,
  title={Multimodal neuroimaging evidence of alterations in cortical structure and function in HIV-infected older adults.},
  author={Tony W. Wilson and Elizabeth Heinrichs-Graham and Katherine M. Becker and Joseph Aloi and Kevin R. Robertson and Uriel S Sandkovsky and Matthew L. White and Jennifer T O'Neill and Nichole L. Knott and Howard S. Fox and Susan S Swindells},
  journal={Human brain mapping},
  year={2015},
  volume={36 3},
  pages={897-910}
}
Combination antiretroviral therapy transformed human immunodeficiency virus (HIV)-infection from a terminal illness to a manageable condition, but these patients remain at a significantly elevated risk of developing cognitive impairments and the mechanisms are not understood. Some previous neuroimaging studies have found hyperactivation in frontoparietal networks of HIV-infected patients, whereas others reported aberrations restricted to sensory cortices. In this study, we utilize high… CONTINUE READING
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