Multimodal nanoprobes evaluating physiological pore size of brain vasculatures in ischemic stroke models.

@article{Zheng2014MultimodalNE,
  title={Multimodal nanoprobes evaluating physiological pore size of brain vasculatures in ischemic stroke models.},
  author={Shuyan Zheng and Ying-ying Bai and Yinzhi Changyi and Xihui Gao and Wenqing Zhang and Yuancheng Wang and Lu Zhou and Shenghong Ju and Cong Bo Li},
  journal={Advanced healthcare materials},
  year={2014},
  volume={3 11},
  pages={1909-18}
}
Ischemic stroke accounts for 80% strokes and originates from a reduction of cerebral blood flow (CBF) after vascular occlusion. For treatment, the first action is to restore CBF by thrombolytic agent recombinant tissue-type plasminogen activator (rt-PA). Although rt-PA benefits clinical outcome, its application is limited by short therapeutic time window… CONTINUE READING