Multimodal imaging in rats reveals impaired neurovascular coupling in sustained hypertension.

@article{Calcinaghi2013MultimodalII,
  title={Multimodal imaging in rats reveals impaired neurovascular coupling in sustained hypertension.},
  author={Novella Calcinaghi and Matthias T. Wyss and Renaud Jolivet and Anand Singh and A. L. Keller and Stephan H Winnik and J. -M. Fritschy and Alfred Buck and Christian M Matter and B. Weber},
  journal={Stroke},
  year={2013},
  volume={44 7},
  pages={1957-64}
}
BACKGROUND AND PURPOSE Arterial hypertension is an important risk factor for cerebrovascular diseases, such as transient ischemic attacks or stroke, and represents a major global health issue. The effects of hypertension on cerebral blood flow, particularly at the microvascular level, remain unknown. METHODS Using the spontaneously hypertensive rat (SHR) model, we examined cortical hemodynamic responses on whisker stimulation applying a multimodal imaging approach (multiwavelength… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 2 times. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 25 extracted citations

Intravital imaging in spontaneously hypertensive stroke-prone rats-a pilot study

Experimental & Translational Stroke Medicine • 2013
View 4 Excerpts
Highly Influenced

A critical role for the ATP-sensitive potassium channel subunit KIR6.1 in the control of cerebral blood flow.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism • 2018

References

Publications referenced by this paper.
Showing 1-10 of 20 references

Metabotropic glutamate receptor mGluR5 is not involved in the early hemodynamic response.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism • 2011

Endothelial function and oxidative stress in cardiovascular diseases.

Circulation journal : official journal of the Japanese Circulation Society • 2009
View 1 Excerpt

Similar Papers

Loading similar papers…