Multimerization of polyomavirus middle-T antigen.

Abstract

The oncogenic protein of polyomavirus, middle-T antigen, associated with cell membranes and interacts with a variety of cellular proteins involved in mitogenic signalling. Middle-T antigen may therefore mimic the function of cellular tyrosine kinase growth factor receptors, like the platelet-derived growth factor or epidermal growth factor receptor. Growth… (More)

Topics

Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.