Multimerin: a series of large disulfide-linked multimeric proteins within platelets.

@article{Hayward1991MultimerinAS,
  title={Multimerin: a series of large disulfide-linked multimeric proteins within platelets.},
  author={Catherine P M Hayward and Theodore E Warkentin and Peter Horsewood and John G. Kelton},
  journal={Blood},
  year={1991},
  volume={77 12},
  pages={2556-60}
}
Platelets contain proteins with biochemical properties that are well adapted to promoting hemostasis. One important adhesive protein is von Willebrand factor (vWF), which is a very large protein comprised of a series of multimers, ranging from 860,000 to over 10 million daltons. In this report we describe a second platelet protein, p-155, which has a similar unique multimeric composition. Using agarose-acrylamide gel electrophoresis, platelet p-155 was shown to be composed of multimers ranging… CONTINUE READING

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References

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Showing 1-9 of 9 references

The complex multimeric composition of factor V l l lhon Willebrand factor

ZM Ruggeri, Zimmerman Ts
Blood • 1981

Zimmennan Ts: Variant von Willebrand's disease: Characterization of two subtypes by analysis of multimeric composition of factor V l l l h n Willebrand factor in plasma and platelets

ZM Ruggeri
J Clin Invest • 1980

Human b l d platelet adhesion to artery subendothelium is mediated by factor V111-von Willebrand factor bound to the subendothelium

PA Sakariassen KS. Bolhuis, JJ Sixma
Nature 279:636 • 1979

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