Multilocus sequence typing--what is resolved?

  title={Multilocus sequence typing--what is resolved?},
  author={Jessica E Cooper and Edward J Feil},
  journal={Trends in microbiology},
  volume={12 8},
Nucleotide sequence-based methods for bacterial typing (multilocus sequence typing; MLST) allow rapid and global comparisons between results from different laboratories. Combining this advantage with the reduced cost of high throughput sequencing, increasing automation and the amenability of sequence data for evolutionary analysis, it seems inevitable that sequence-based typing will eventually predominate over gel-based methods such as pulsed-field gel electrophoresis (PFGE) for most bacterial… CONTINUE READING
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