Multilocus genotypic association with vascular dementia by multifactor dimensionality reduction and entropy-based estimation.

OBJECTIVE We conducted a simultaneous analysis of candidate genetic loci for their genotypic association with the susceptibility to vascular dementia (VaD) to put forth the best model for predicting genetic susceptibility to VaD. METHODS Individual-locus effects and their epistatic effects on susceptibility to VaD were simultaneously assessed by… CONTINUE READING