Multilign: an algorithm to predict secondary structures conserved in multiple RNA sequences

@article{Xu2011MultilignAA,
  title={Multilign: an algorithm to predict secondary structures conserved in multiple RNA sequences},
  author={Zhenjiang Xu and David H. Mathews},
  journal={Bioinformatics},
  year={2011},
  volume={27 5},
  pages={
          626-32
        }
}
MOTIVATION With recent advances in sequencing, structural and functional studies of RNA lag behind the discovery of sequences. Computational analysis of RNA is increasingly important to reveal structure-function relationships with low cost and speed. The purpose of this study is to use multiple homologous sequences to infer a conserved RNA structure. RESULTS A new algorithm, called Multilign, is presented to find the lowest free energy RNA secondary structure common to multiple sequences… CONTINUE READING

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