Multilevel Control of Arabidopsis 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase by Protein Phosphatase 2A[W]

@article{Leivar2011MultilevelCO,
  title={Multilevel Control of Arabidopsis 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase by Protein Phosphatase 2A[W]},
  author={P. Leivar and Meritxell Antol{\'i}n-Llovera and S. Ferrero and Marta Closa and M. Arr{\'o} and A. Ferrer and A. Boronat and N. Campos},
  journal={Plant Cell},
  year={2011},
  volume={23},
  pages={1494 - 1511}
}
HMG-CoA reductase has a key role in the regulation of the mevalonate pathway for isoprenoid biosynthesis and is modulated by many diverse endogenous and environmental stimuli. In this work, protein phosphatase 2A emerges as a positive and negative multilevel regulator of plant HMG-CoA reductase during normal development and in response to a variety of stress conditions. Plants synthesize a myriad of isoprenoid products that are required both for essential constitutive processes and for adaptive… Expand
79 Citations
An Overview of 3-Hydroxy-3-Methylglutaryl CoA Reductase (HMGR) in Plants
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Determination of 3-hydroxy-3-methylglutaryl CoA reductase activity in plants.
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Post-translational events and modifications regulating plant enzymes involved in isoprenoid precursor biosynthesis.
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