Multilayered heparin hydrogel microwells for cultivation of primary hepatocytes.

@article{You2014MultilayeredHH,
  title={Multilayered heparin hydrogel microwells for cultivation of primary hepatocytes.},
  author={Jungmok You and Dong-Sik Shin and Dipali Dhanji. Patel and Yandong Gao and Alexander Revzin},
  journal={Advanced healthcare materials},
  year={2014},
  volume={3 1},
  pages={
          126-32
        }
}
The biomaterial scaffolds for regenerative medicine need to be rationally designed to achieve the desired cell fate and function. This paper describes the development of hydrogel microstructures for cultivation of primary hepatocytes. Four different micropatterned surfaces are tested: 1) poly(ethyelene glycol) (PEG) microwells patterned on glass, 2) heparin hydrogel microwells patterned on glass, 3) PEG microwells patterned on heparin hydrogel-coated substrates, and 4) heparin hydrogel… CONTINUE READING
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