Multilayer sodium alginate beads with porous core containing chitosan based nanoparticles for oral delivery of anticancer drug.

@article{Li2016MultilayerSA,
  title={Multilayer sodium alginate beads with porous core containing chitosan based nanoparticles for oral delivery of anticancer drug.},
  author={Jing Li and Changqing Jiang and Xuqian Lang and Ming Kong and Xiaojie Cheng and Ya Liu and Chao Feng and Xi Chen},
  journal={International journal of biological macromolecules},
  year={2016},
  volume={85},
  pages={1-8}
}
To develop efficient and safe anticancer drug doxorubicin hydrochloride (DOX) delivery system for oral chemotherapy, chitosan based nanoparticles (CS/CMCS-NPs) composed of chitosan (CS) and o-carboxymeymethy chitosan (CMCS) were immobilized in multilayer sodium alginate beads (NPs-M-Beads). Two kinds of NPs-M-Beads, with or without porous core, were… CONTINUE READING