Multilaboratory assessment of threshold versus fold-change algorithms for minimizing analytical variability in multiplexed pneumococcal IgG measurements.

Abstract

Pneumococcal vaccination is frequently used to assess a patient's humoral immune function. The comparison of pre- and postvaccination levels of antipneumococcal antibodies is widely held to be the gold standard for documenting a response. However, many of the published criteria for defining an adequate response are based on assays that are no longer widely… (More)
DOI: 10.1128/CVI.00235-14

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@article{Daly2014MultilaboratoryAO, title={Multilaboratory assessment of threshold versus fold-change algorithms for minimizing analytical variability in multiplexed pneumococcal IgG measurements.}, author={Thomas M. Daly and Jerry W. Pickering and Xiaochun Zhang and Harry E. Prince and Harry Raymond Hill}, journal={Clinical and vaccine immunology : CVI}, year={2014}, volume={21 7}, pages={982-8} }