Multiinstitutional validation of the UCSF cancer of the prostate risk assessment for prediction of recurrence after radical prostatectomy

@article{Cooperberg2006MultiinstitutionalVO,
  title={Multiinstitutional validation of the UCSF cancer of the prostate risk assessment for prediction of recurrence after radical prostatectomy},
  author={Matthew R. Cooperberg and Stephen J. Freedland and David J. Pasta and Eric P. Elkin and Joseph Presti and Christopher L Amling and Martha K. Terris and William J. Aronson and Christopher J. Kane and Peter R. Carroll},
  journal={Cancer},
  year={2006},
  volume={107}
}
The University of California, San Francisco (UCSF) Cancer of the Prostate Risk Assessment (CAPRA) is a novel preoperative index which predicts the risk of biochemical recurrence after radical prostatectomy. The performance of the index is at least as good as the best available instruments based on clinical variables, and the 0 to 10 score is simple to calculate for both clinical and research purposes. This study used a large external dataset to validate CAPRA. 
Validity of the CAPRA score to predict biochemical recurrence-free survival after radical prostatectomy. Results from a european multicenter survey of 1,296 patients.
TLDR
The results underscore the effectiveness and the clinical applicability of the CAPRA score which, in addition to patient counseling, may also be used for risk stratification in clinical studies. Expand
External validation of University of California, San Francisco, Cancer of the Prostate Risk Assessment score.
TLDR
The UCSF-CAPRA performed well in this tertiary, referral-based cohort with a c-index similar to that of the Kattan nomogram and remains an effective prognostic instrument for predicting the risk of biochemical recurrence after radical prostatectomy. Expand
External validation of the UCSF-CAPRA (University of California, San Francisco, Cancer of the Prostate Risk Assessment) in Japanese patients receiving radical prostatectomy.
TLDR
The UCSF-CAPRA is an acceptable risk category tool comparable to that of the D'Amico risk classification for Japanese prostate cancer patients receiving radical prostatectomy in the contemporary Gleason grading era. Expand
External validation of the cancer of the prostate risk assessment (CAPRA) score in a single-surgeon radical prostatectomy series.
TLDR
The results validate the UCSF-CAPRA score as a significant predictor of 5-year PFS in a single surgeon series and show that the CAPRA score is a simple preoperative tool that can be readily applied in clinical practice to help risk-stratify prostate cancer patients. Expand
Multi-institutional validation of the CAPRA-S score to predict disease recurrence and mortality after radical prostatectomy.
TLDR
In this external validation, the CAPRA-S score predicted recurrence and mortality after RP with a c-index >0.70 and is an effective prognostic tool that may aid in determining the need for adjuvant therapy. Expand
A Straightforward Tool for Improved Prediction of Outcomes After Radical Prostatectomy
TLDR
The new postsurgical score (CAPRA-S) offers good discriminatory accuracy, calibration, and ease of calculation for clinical and research settings and performed better in both calibration and decision curve analyses. Expand
External validation of the Briganti nomogram to estimate the probability of specimen‐confined disease in patients with high‐risk prostate cancer
TLDR
An external validation of the updated nomogram from Briganti et’al. Expand
External Validation of the Cancer of the Prostate Risk Assessment Score to Predict Biochemical Relapse after Radical Prostatectomy for Prostate Cancer in Japanese Patients
TLDR
In Japanese patients, the CAPRA score can predict BCR after RP only to some degree, and its c-index is lower than the c-indices reported in other validation cohorts, which range from 0.68 to 0.81. Expand
Prognostic value of the CAPRA clinical prediction rule: a systematic review and meta‐analysis
TLDR
A systematic review examines the totality of evidence in relation to the predictive value of the CAPRA clinical predication rule by combining all studies that validate the rule. Expand
ncology xternal Validation of University of alifornia , San Francisco , Cancer of the rostate Risk Assessment
BJECTIVES In 2005, the University of California, San Francisco, proposed the Cancer of the Prostate Risk Assessment (UCSF-CAPRA) score to predict the risk of biochemical recurrence (BR) after radicalExpand
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