Multigene family for sarcomeric myosin heavy chain in mouse and human DNA: localization on a single chromosome.

@article{Leinwand1983MultigeneFF,
  title={Multigene family for sarcomeric myosin heavy chain in mouse and human DNA: localization on a single chromosome.},
  author={L. A. Leinwand and R. E. Keith Fournier and B Nadal-Ginard and T. B. Shows},
  journal={Science},
  year={1983},
  volume={221 4612},
  pages={766-9}
}
Cloned myosin heavy chain DNA probes from rat and human were hybridized to restriction endonuclease digests of genomic DNA from somatic cell hybrids and their parental cells. The mouse myosin heavy chain genes detectable by this assay were located on chromosome 11, and three different human sarcomeric myosin heavy chain genes were mapped to the short arm of chromosome 17. A synteny between myosin heavy chain and two unrelated markers, thymidine kinase and galactokinase, was found to be… CONTINUE READING

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