Multifunctionalized polyethyleneimine-based nanocarriers for gene and chemotherapeutic drug combination therapy through one-step assembly strategy

@inproceedings{Jiang2017MultifunctionalizedPN,
  title={Multifunctionalized polyethyleneimine-based nanocarriers for gene and chemotherapeutic drug combination therapy through one-step assembly strategy},
  author={DanDan Jiang and Mingfang Wang and Tianqi Wang and Bo Zhang and Chunxi Liu and Na Zhang},
  booktitle={International journal of nanomedicine},
  year={2017}
}
Gene therapy combined with chemotherapy to achieve synergistic therapeutic effects has been a hot topic in recent years. In this project, the human tumor necrosis factor-related apoptosis-inducing ligand-encoding plasmid gene (TRAIL) and doxorubicin (Dox)-coloaded multi-functional nanocarrier was constructed based on the theory of circulation, accumulation, internalization, and release. Briefly, polyethyleneimine (PEI) was selected as skeleton material to synthesize PEI-polyethylene glycol (PEG… CONTINUE READING

Citations

Publications citing this paper.

References

Publications referenced by this paper.
SHOWING 1-10 OF 47 REFERENCES

Adeno-associated virus (AAV) vectors in cancer gene therapy.

  • Journal of controlled release : official journal of the Controlled Release Society
  • 2016
VIEW 1 EXCERPT

Polymer-coated pH-responsive high-density lipoproteins.

  • Journal of controlled release : official journal of the Controlled Release Society
  • 2016
VIEW 1 EXCERPT