Multifunctionalization of alkenes via aerobic oxynitration and sp3 C-H oxidation.

@article{Taniguchi2013MultifunctionalizationOA,
  title={Multifunctionalization of alkenes via aerobic oxynitration and sp3 C-H oxidation.},
  author={Tsuyoshi Taniguchi and Yuki Sugiura and Takashi Hatta and Atsushi Yajima and Hiroyuki Ishibashi},
  journal={Chemical communications},
  year={2013},
  volume={49 22},
  pages={2198-200}
}
A method for direct functionalization of three positions including an unactivated C-H bond of aliphatic alkenes using tert-butyl nitrite and molecular oxygen to give γ-lactols has been developed. The present reaction proceeds through a sequence of radical processes involving oxynitration followed by aerobic oxidation of an sp(3) C-H bond. This… CONTINUE READING