Multifunctional roles of insulin-like growth factor binding protein 5 in breast cancer

@article{Akkiprik2008MultifunctionalRO,
  title={Multifunctional roles of insulin-like growth factor binding protein 5 in breast cancer},
  author={Mustafa Akkiprik and Yumei Feng and Huamin Wang and Kexin Chen and Limei Hu and Aysegul A. Sahin and Savitri Krishnamurthy and A Nevra Ozer and Xishan Hao and Wei Zhang},
  journal={Breast Cancer Research : BCR},
  year={2008},
  volume={10},
  pages={212 - 212}
}
The insulin-like growth factor axis, which has been shown to protect cells from apoptosis, plays an essential role in normal cell physiology and in cancer development. The family of insulin-like growth factor binding proteins (IGFBPs) has been shown to have a diverse spectrum of functions in cell growth, death, motility, and tissue remodeling. Among the six IGFBP family members, IGFBP-5 has recently been shown to play an important role in the biology of breast cancer, especially in breast… CONTINUE READING
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