Multifunctional roles of Saccharomyces cerevisiae Srs2 protein in replication, recombination and repair.

@article{Niu2017MultifunctionalRO,
  title={Multifunctional roles of Saccharomyces cerevisiae Srs2 protein in replication, recombination and repair.},
  author={Hengyao Niu and Hannah L. Klein},
  journal={FEMS yeast research},
  year={2017},
  volume={17 2}
}
The Saccharomyces cerevisiae Srs2 DNA helicase has important roles in DNA replication, recombination and repair. In replication, Srs2 aids in repair of gaps by repair synthesis by preventing gaps from being used to initiate recombination. This is considered to be an anti-recombination role. In recombination, Srs2 plays both prorecombination and anti-recombination roles to promote the synthesis-dependent strand annealing recombination pathway and to inhibit gaps from initiating homologous… CONTINUE READING
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References

Publications referenced by this paper.
Showing 1-10 of 37 references

Avoidance of ribonucleotide-induced mutations by RNase H2 and Srs2-Exo1 mechanisms. Nature

CJ Potenski, H Niu, P Sung, HL Klein
Nat Commun • 2014
View 10 Excerpts
Highly Influenced

Srs2 mediates PCNA-SUMO-dependent inhibition of DNA repair synthesis

The EMBO journal • 2013
View 3 Excerpts
Highly Influenced

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